Development and validation of the method for the determination of clofibric acid by gas chromatography mass

Authors

  • Manuel Sánchez Zarza
  • Martha Avilés Flores
  • Luis Alberto González Esquivel

DOI:

https://doi.org/10.35197/rx.08.02.e.2012.15.ms

Keywords:

trimethylsilyldiazomethicone, clofibric acid, validation

Abstract

A methodology for the quantification of trimethylsilyldiazomethane-derivatized clofibric acid in water samples was developed and validated by gas chromatography coupled to a mass selective detector (GC-MS). The method was validated in different parameters such as linearity, accuracy, precision, detection and quantification limits. The validation concentrations are in the range of 0.0025 to 0.1644 μgL-1. The detection and quantification limits obtained are 0.0003 and 0.0053 μgL-1.

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Published

2012-08-31

How to Cite

Sánchez Zarza, M., Avilés Flores, M., & González Esquivel, L. A. (2012). Development and validation of the method for the determination of clofibric acid by gas chromatography mass. Revista Ra Ximhai , 8(2 Especial). https://doi.org/10.35197/rx.08.02.e.2012.15.ms

Issue

Vol. 8 No. 2 Especial (2012): Mayo - Agosto

Section

Artículos científicos

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Copyright (c) 2012 Manuel Sánchez Zarza, Martha Avilés Flores, Luis Alberto González Esquivel

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